Deformulation and reverse engineering

Absolute Laboratories provides independent analytical testing services, with customizable analysis procedures available, to unravel a specific formula, material or, in certain circumstances, process sequence. Our instrumentation combined with proprietary scientific methodologies allow Absolute Labs to provide you with powerful information. Absolute Labs analytical testing services include detection and measurement of elemental, ionic, molecular, biological and mechanical parameters – revealing even ultratrace details.

Reverse engineering can be used to determine active agents in chemical formulations, competitive product analysis, understanding proprietary formulations, infringement by competitors, or intellectual property investigations.

Request a quote now by clicking here and an analytical specialist will promptly review your project and respond with the next steps.

Analytical Testing Capabilities

DRIFTS Diffuse Reflectance Infrared Fourier Transform Spectrometry services provide for rapid identification of bulk and trace residues. Field sampling kits are available to ensure reliable sample collection, rapid analysis and identification.
Electrometric Methods. Includes a variety of electrode based measurements including selective ion analysis, half electrodes, solid state sensors, micro-seimens, uMOHMs, ORP, dissolve gases physical environmental measurements,  real time remote measurement,  ambient gases, corrosive agents and physio-chemical paramenters. Orion, YSI, Beckman, Tekna, and other systems.
UV/VIS Spectrophotometry. Research grade instrumentation and acquisition control software for standard absorption or transmission spectra for quantitation, quality control, kinetic, enzymatic and proteomic analysis. Beckman systems.
Atomic Absorption Spectrophotometry (AAS). State of the art system with Graphite Furnace Accessory (GFA) with Zeeman correction capability. Services provide trace detection of single and multiple elemental analyses. Ultra-trace detection for routine analysis at sub ppb concentrations. Varian systems.
Inductively Coupled Argon Plasma Emission Spectrometry (ICAPES). Rapid analysis of complex multi-element solids, liquids or gas matrices. Excellent choice of determining elemental composition of known, unknown materials and general contaminant characterization. Leeman systems.
Gas Chromatography (GC). Specializing in variety of standard and high resolution gas chromatographic analytical methods used for the identification of an immense spectrum of compounds ranging from permanent gases ( Ar, He, H₂, O₂, N₂, CH₄, CO, CO₂) to macromolecular substances. The use of selective detectors allows for rapid detection of trace substances in a the proverbial haystack. GC-ECD, GC-FID. GC-PID, GC-MS, GC-TCD, GC-PD, Py-GC, SHS-GC,  HS-GC and related ancillary methodology. Varian, HP, CDS and SRI  chromatography systems.
Capillary Electrophoretic (CE) Methods. Capillary Zone Electrophoresis (CZE). Micellar Electrophoresis. Coupled with UV detectors, Diode Array Detection, LASER Fluorescence and Excitation detection. cIEF Capillary Iso-Electric Focusing, MEKC Micellar Electro-Kinetic Chromatography, CZE Capillary Zone Electrophoresis, CGE Capillary Gel Electrophoresis, CITP Capillary Isotachophoresis, OTCEC Open Tubular Capillary Electrochromatography, CEC Capillary Electro-Chromatography. CE is suited for rush analysis of a wide variety of analytes ranging from cations and anion to macromolecules. Ideal for labile substances that cannot withstand the operational conditions of gas chromatograph testing environments. Beckman spectroscopy systems.
High Pressure Liquid Chromatography (HPLC). Normal, reverse phases, DVB and microbore capabilities. Detection via UV, DAD, and conductivity modes. Anions, cations, organic substances. HP, LBK, Dionex chromatographic systems.
Optical Microscopy. Macro and high magnification optical, phase contrast, polarized light,  DIC, and  fluorescence microscopy. The most commonly applied technique in particle identification is optical microscopy and digital micrographs. It is inexpensive, quick, and, when done with a trained eye, identifies the largest number of contaminant particles. With experience, a microscopist can recognize a specific particle on sight. Physical characteristics such as shape, size, color, texture and optical properties are used for identification.  Other methods involve subject materials that are  illuminated with light of a specific wavelength (or wavelengths) which is absorbed by the fluorophores, causing light emission of longer wavelengths (i.e., of a different color than the absorbed light). The illumination light is separated from the much weaker emitted fluorescence through the use of a spectral emission filter. Fluorophores can be  used to label specimens in this manner, the distribution of a single fluorophore (color) is imaged at a time. Multi-color images of several types of fluorophores must be composed by combining several single-color images. Fluorescence microscopes are epifluorescence microscopes, where excitation of the fluorophore and detection of the fluorescence are done through the same light path (i.e. through the objective). Olympus and Nikon microscopy micro-photographic and associated software systems.
Electron Microscopy methods include SEM, SAEDX, TEM for measurement, elemental composition and identification of crystalline, metallic and some organic materials. The techniques used to count particles in a scanning electron microscope (SEM) are similar to those used to count with a light microscope. Often the subject material is sampled onto a membrane filter with the collected sample in the SEM and counts a minimum of 500 particles.Using an energy dispersive X-ray analysis system,the operator can identify the elements present in the particles. Useful  particles and fibers as small as 0.3- 2 nanometers.  Hitachi system.

Request a quote now by clicking here and an analytical specialist will promptly review your project and respond with the next steps.